Every possible doubt about Covid vaccine cleared by Dr. Reshma Hingorani
What is the recommended dose and schedule?
Do you need to take it even if you had Corona?
How many days after getting vaccine, would I develop protection?
How long will the vaccine provide immunity?
When is the Corona vaccine likely to be available in India?
These and many more questions answered.
- What is the recommended dose and schedule?
Two doses given 21 days or 28 days apart depending on vaccine used.
- What if I take only one dose?
One dose will give you only partial protection of maybe 60-80% and will not last long enough. For complete protection you must take two doses at recommended intervals.
- What if I forget to take the second dose? Should I take the first again?
Just take the second dose at the earliest. No need to repeat the first dose.
- Are both doses same?
In most of the vaccines it will be the same dose given twice. However, Sputnik- V vaccine has both doses as different vector viruses, so will be marked as dose 1 and 2. Oxford-AZ vaccine may also come out with first dose as half dose.
- Do you need to take it even if you had Corona? After how many days of getting cured?
Yes. But that will be last in the priority list. You can let others take who probably need more than you. You might need it earlier if you did not develop an antibody response.
- Can it be administered to an individual who has received plasma as treatment for Covid?
The donor plasma contains anti Covid-19 antibodies and may suppress the immune response to the vaccine. As it is, those who have recovered from Covid-19 may not need the vaccine in the early phases.
- Can a pregnant lady or a lactating mother take the vaccine?
No company has yet tested the vaccine in pregnancy. CDC has advised against giving the vaccine to pregnant and lactating mothers. UK authorities have advised women not to get pregnant for two months after the shot. Since the vaccines available till now are not live vaccines, it should not cause any problem if given inadvertently.
- Can a diabetic patient take the vaccine?
Yes, in fact diabetes has been established as a risk factor for severe disease and all diabetic patients must get vaccinated on priority.
- If offered a choice of vaccines, which one should I take?
All vaccines are offering equal efficacy although local reactions may be different. Take whatever available. Think positive that at least you are being offered a vaccine ahead of others. Indian manufactured vaccines will be more suitable for our population as they are cheaper and can be kept at 2-8 degree Celsius. The mRNA vaccines require a storing temp of -70 (Pfizer) and -20 (Moderna) which may be difficult to maintain in summer months.
- How many days after getting vaccine, would I develop protection?
It takes time for your body to build protection after any vaccination. COVID-19 vaccines that require 2 shots may not protect you until a week or two after your second shot.
- How long will the vaccine provide immunity?
It is a new virus, new technology vaccine, so we don’t know. After follow-ups of these vaccinated population and their antibodies for a couple of years, we would be wiser. The need for boosters and when will they be required, will be decided after these follow ups and mathematical modelling.
- Children of what age can be vaccinated? Is the dose same as adults or lesser dose to be given?
Trials done till now have been for adults above 18 only. Now trials for children above 12 have started. Doses will be decided only after trials are done on younger children and infants.
- Can it be given to immunocompromised individuals?
The mRNA vaccine and inactivated vaccines are safe. AZ and Sputnik-V adenovirus vector vaccines are also safe as they are nonreplicating viral vector vaccines. Live vaccines and replicating viral vector vaccines will have to be avoided.
- What are the side effects expected?
The side effects reported by the trial population are mostly mild Covid like symptoms like some fever and fatigue. Local injection site pain and induration is also reported. Reports of transverse myelitis and facial palsy have not been found to be related to the vaccine. Generally, all vaccines are safe. Although these vaccines have been made in record time, the testing methodology and procedures have not been compromised.
- I am allergic to egg. Can I take the vaccine?
Egg cell lines are not used for production of these vaccines. They can be taken safely even if you are allergic to egg.
- I heard that it has pig or monkey products? I am a pure Vegetarian.
The new vaccines manufactured these days are devoid of any such products.
- In the past vaccines have been linked to Autism. What about these?
In 1985 there was a paper linking MMR with autism. Millions of children followed up after that have conclusively proven that there is no relationship between vaccines and autism. All vaccines are extremely safe with minimal temporary side effects.
- There are messages going around that mRNA from vaccine gets incorporated into the human genome and alter our genetic structure. Is that true?
mRNA vaccine carries a message to the cell to produce spike protein which induces antibody production. It does what it is directed to do. Till date there have been no adverse events reported.
- What is the interaction of alcohol and Covid vaccine?
Excessive alcohol can reduce the immune responses to vaccines. Since Russians are known for heavy drinking, their government has advised to avoid drinking two weeks prior to first dose and 6 weeks after the second dose. The Sputnik vaccine is given as two doses 21 days apart. Occasional glass of wine or beer will not interfere with the immune response.
- Soon the virus will mutate and we will need another vaccine. Should we not wait?
Till now the virus has not shown tendency to mutate like the Flu virus. Moreover, the vaccines being developed have taken this into consideration and should still work.
- What if I do not want to take the vaccine? Will it be made mandatory?
In majority of countries, it will not be mandatory. You have to choose between the new viral disease with no specific treatment and a new vaccine. Choice is yours. As initially there will be a huge demand supply gap, by not taking a vaccine you can help others.
- Can I roam around without a mask once I am vaccinated?
No, not as of now. One may do so only when the majority of the population has either got the disease or received the vaccine. This means the population has developed herd immunity.
- Are newer and better Covid vaccines expected in near future?
As of December 2020, more than 250 vaccines are under trial in different phases. A lot of research is underway to develop newer delivery methods also. Nasal spray vaccine is probably the most promising. A multi dose nasal spray delivery device can be very convenient and economical. It will produce local IgA antibodies and block the virus at entry itself. It will reduce nasal colonisation and thus prevent transmission of disease also. Unfortunately, since it will be a live vaccine, it will need maximum and most stringent trials and thus will take longest time to hit the market. Covid-19 is still a new disease and we are still learning. The facts mentioned above are as of 14 December 2020. Please re-check the facts before taking a Covid vaccine shot.
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